• Users Online: 844
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
Year : 2015  |  Volume : 12  |  Issue : 2  |  Page : 136-141

The relation of gender and geometry to left ventricular structure and functions in a newly presenting hypertensive population in Nigeria

1 Department of Medicine, University of Ibadan; Department of Medicine, University College Hospital, Ibadan, Nigeria
2 Department of Medicine, University College Hospital, Ibadan, Nigeria
3 Department of Medicine, University of Ibadan, Ibadan, Nigeria

Correspondence Address:
Abiodun M Adeoye
Department of Medicine, University of Ibadan, Ibadan
Login to access the Email id

Source of Support: None, Conflict of Interest: None

DOI: 10.4103/0189-7969.161777

Rights and Permissions

Background: Studies differ on the influence of gender and geometry on the functions of left ventricle (LV). We report the relation of abnormal geometry and gender to LV structure and functions in an African population. Materials and Methods: A total of 156 consecutive newly presenting hypertensives comprising 53% females were enrolled into the study. All participants underwent full clinical evaluation, and echocardiographic examination was performed according to the American Society of echocardiography recommendation. Using LV mass index (LVMI) and relative wall thickness, 145 subjects with complete echocardiographic parameters were divided into four LV geometric patterns; normal, concentric remodelling (CR), eccentric hypertrophy, and concentric hypertrophy. Results: The mean age of the hypertensive subjects was 59.5 (12.3) years. The mean age and blood pressure (BP) indices were comparable across the gender. While males were taller, females were heavier and had wider waist and hip circumferences. Men had larger left atrium, aortic root diameter, aortic valvular opening, LV dimensions, and LVM compared with females. LV systolic and diastolic functions were similar. More than half of the subjects had abnormal geometry with CR prevalent. The subjects with concentric hypertrophy were the youngest (P = 0.036) and had the highest mean diastolic BP (P = 0.037). There was no significant gender influence on the distribution of geometry pattern. Left Atrial diameter and LV dimensions except posterior wall thickness at diastole were significantly larger in eccentric hypertrophy when compared with other groups (P = 0.0001). LV ejection fraction was lowest among subjects with eccentric hypertrophy. Diastolic function parameters were comparable among the groups. Conclusion: The study showed that more than half of the study subjects had abnormal geometry even at the presentation. Abnormal geometry probably affects LV systolic function more than the diastolic filling patterns. Prompt management may alter the prognostic effect of abnormal geometry among the study group.

Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)

 Article Access Statistics
    PDF Downloaded191    
    Comments [Add]    

Recommend this journal