Year : 2019 | Volume
: 16 | Issue : 1 | Page : 25--31
Serum chemerin as a predictor of left ventricle hypertrophy in patients with coronary artery disease
Noha Hasssanin Hanboly1, Yasser Sharaf1, Mervat Al-Anany2, Essam Saeed1
1 Department of Cardiovascular Diseases, Faculty of Medicine, Cairo University, Cairo, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt
Background: Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular risk and its detection contributes to risk stratification. Chemerin is a secreted protein with a complex but well-established role in immune function. It regulates adipocyte development and metabolic function as well as glucose metabolism in liver and skeletal muscle tissues.
Purpose of the Study: The aim of the current study was to investigate the correlation between the serum chemerin level and occurrence of LVH in patients with coronary artery disease (CAD).
Patients and Methods: The study included 100 patients with CAD. Patients were classified according to their body mass index (BMI) into two groups, 50 patients (Group A) with BMI (≥30 kg/m2) and 50 patients (Group B) with BMI ≤25 kg/m2. Transthoracic echocardiography was done for all patients after a thorough clinical assessment. Left ventricular study was done according to the guidelines endorsed by the American society of echocardiography.
Results: Serum chemerin level was positively correlated with BMI, waist circumference, and left ventricle mass index (P < 0.005 for all).
Conclusion: Serum chemerin levels were higher in obese patients with CAD. Levels were associated with LVH and increased high-sensitivity C-reactive protein as a marker of inflammation.
Prof. Noha Hasssanin Hanboly
Department of Cardiovascular Diseases, Cairo University, Cairo
|How to cite this article:|
Hanboly NH, Sharaf Y, Al-Anany M, Saeed E. Serum chemerin as a predictor of left ventricle hypertrophy in patients with coronary artery disease.Nig J Cardiol 2019;16:25-31
|How to cite this URL:|
Hanboly NH, Sharaf Y, Al-Anany M, Saeed E. Serum chemerin as a predictor of left ventricle hypertrophy in patients with coronary artery disease. Nig J Cardiol [serial online] 2019 [cited 2020 Jul 13 ];16:25-31
Available from: http://www.nigjcardiol.org/article.asp?issn=0189-7969;year=2019;volume=16;issue=1;spage=25;epage=31;aulast=Hanboly;type=0