• Users Online: 929
  • Home
  • Print this page
  • Email this page
Home About us Editorial board Search Ahead of print Current issue Archives Submit article Instructions Subscribe Contacts Login 
ORIGINAL ARTICLE
Year : 2019  |  Volume : 16  |  Issue : 1  |  Page : 25-31

Serum chemerin as a predictor of left ventricle hypertrophy in patients with coronary artery disease


1 Department of Cardiovascular Diseases, Faculty of Medicine, Cairo University, Cairo, Egypt
2 Department of Clinical Pathology, Faculty of Medicine, Cairo University, Cairo, Egypt

Correspondence Address:
Prof. Noha Hasssanin Hanboly
Department of Cardiovascular Diseases, Cairo University, Cairo
Egypt
Login to access the Email id

Source of Support: None, Conflict of Interest: None


DOI: 10.4103/njc.njc_20_18

Rights and Permissions

Background: Left ventricular hypertrophy (LVH) is an important predictor of cardiovascular risk and its detection contributes to risk stratification. Chemerin is a secreted protein with a complex but well-established role in immune function. It regulates adipocyte development and metabolic function as well as glucose metabolism in liver and skeletal muscle tissues. Purpose of the Study: The aim of the current study was to investigate the correlation between the serum chemerin level and occurrence of LVH in patients with coronary artery disease (CAD). Patients and Methods: The study included 100 patients with CAD. Patients were classified according to their body mass index (BMI) into two groups, 50 patients (Group A) with BMI (≥30 kg/m2) and 50 patients (Group B) with BMI ≤25 kg/m2. Transthoracic echocardiography was done for all patients after a thorough clinical assessment. Left ventricular study was done according to the guidelines endorsed by the American society of echocardiography. Results: Serum chemerin level was positively correlated with BMI, waist circumference, and left ventricle mass index (P < 0.005 for all). Conclusion: Serum chemerin levels were higher in obese patients with CAD. Levels were associated with LVH and increased high-sensitivity C-reactive protein as a marker of inflammation.


[FULL TEXT] [PDF]*
Print this article     Email this article
 Next article
 Previous article
 Table of Contents

 Similar in PUBMED
   Search Pubmed for
   Search in Google Scholar for
 Related articles
 Citation Manager
 Access Statistics
 Reader Comments
 Email Alert *
 Add to My List *
 * Requires registration (Free)
 

 Article Access Statistics
    Viewed204    
    Printed8    
    Emailed0    
    PDF Downloaded21    
    Comments [Add]    

Recommend this journal